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New publications! Our manuscript describing the mechanism by which the small molecule chaperone Ambroxol inhibits the co-assembly of alpha-synuclein with lipids into amyloid fibrils is now published at Chemical Science Journal. This collaborative work with Jesper Dreier, Elliot Carles, Katharina Schott, Alisdair Stevenson and Thomas Michaels suggests a novel role of Ambroxol that can act […]
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On the 10-year anniversary of the National Centre for Excellence in Research on Parkinson’s Disease (NCER-PD) Céline, Krista and Kathi joined the celebratory conference in Luxembourg. Céline gave a talk on our latest findings on lipid changes associated with PD in post-mortem brain samples as well as the newly discovered inhibitory effect of Ambroxol on aS aggregation. Krista gave a […]
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Together with her consortium partners (Lucie Khemtemourian, Birgit Strodel, Gunnar Schröder, Christian Griesinger, Rita Guzzi, Anna Erlandsen and Carmelo La Rosa) Céline will receive funding from the European Research Executive Agency for a MSCA doctoral programme with the project “From biophysical chemistry to cell biology: Deciphering the role of lipids in the toxicity and spreading […]
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Céline received a 11.4 Mio DKK Hallas-Møller Ascending Investigator grant from the Novo Nordisk foundation for the project entitled “Reverting brain lipid changes associated with Parkinson’s Disease pathology in patients’ neuronal cells”. This project aims at testing novel strategies to revert lipid changes associated with Parkinson’s Disease and decrease protein clumps in neuronal cells. Read […]
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Prof. Daniel Otzen (Main PI), Prof. Nikos Hatzakis (co PI), Prof. Martin Lauritzen (co PI) and Céline were awarded a 20 Mio DKK Collaborative Project grant from the Lundbeck foundation for the project “NanoPANS (Functionalized Nanocarriers sending anti-PARkinson’s Disease drugs to the Nervous System)”. This project aims at developing and testing innovative methods to transport […]
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Céline received a 3.4 Mio DKK grant from the Novo Nordisk foundation for the project “Characterizing Parkinson’s Disease pathological proteomic changes at the aggregate level.” This project aims to quantify changes in protein levels associated with Parkinson’s Disease and related disruptions in lipid metabolism in post-mortem brain samples. This project involves a collaboration with Assoc. […]
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The ISBUC Annual Meeting is a full-day event fostering interdisciplinary exchange among structural biologists, highlighting the latest advancements and integrative approaches in the field. This year, Jesper Elmsted Dreier made a standout contribution with his poster, earning him the Best Poster Award. Congratulations to Jesper for his great work and the well deserved prize!



