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Céline received a 3.4 Mio DKK grant from the Novo Nordisk foundation for the project “Characterizing Parkinson’s Disease pathological proteomic changes at the aggregate level.” This project aims to quantify changes in protein levels associated with Parkinson’s Disease and related disruptions in lipid metabolism in post-mortem brain samples. This project involves a collaboration with Assoc. Prof. Erwin Schoof at DTU. https://www.linkedin.com/feed/update/urn:li:activity:7290303097107615744/
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On January 6th, France celebrates the Festival of the Kings with the traditional Galette des Rois—a delicious cake made of flaky puff pastry filled with rich almond frangipane. Hidden inside is a small figurine, and whoever finds it in their slice is crowned king or queen for the day! In Galvagnion group we celebrated this day and enjoyed some cake. This year’s lucky queen was Krista, who graciously appointed Kathi as her co-ruler! Congratulations to both!
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Just before Christmas, the Galvagnion Group came together for a fun-filled team-building day! We kicked things off with a mini golf tournament, filled with laughter, friendly competition, and a few surprise trick shots. After the game, we enjoyed a delicious dinner, sharing stories and celebrating a great year. It was the perfect way to strengthen our team spirit and head into the holidays on a high note. Special thanks to Krista and Jesper for organising this wonderful evening! Here’s to another successful year ahead—Happy Holidays from all of us at Galvagnion Group!
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The ISBUC Annual Meeting is a full-day event fostering interdisciplinary exchange among structural biologists, highlighting the latest advancements and integrative approaches in the field. This year, Jesper Elmsted Dreier made a standout contribution with his poster, earning him the Best Poster Award. Congratulations to Jesper for his great work and the well deserved prize!
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In this study, we discovered the shared lipid signature associated with long sporadic Parkinson’s disease (PD) (sPD), GBA risk and mild mutations, that is distinct from that of GBA severe mutation in PD amygdala. Moreover, we found that the levels of pathological alpha-synuclein, glucocerebrosidase activity and specific lipids, inc. cholesterol, sphingolipids, cardiolipin and diacylglycerides, correlate in sPD samples. These results provide the first evidence that GBA risk/mild mutations, on one hand, and GBA severe mutation, on the other hand, lead to opposite changes in the lipidome of PD amygdala. Finally, we provide the lipid composition of Lewy Bodies (LBs) and small aggregates (SAs) enriched fractions from PD and…
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Jesper, Krista, Celine, and Kathi proudly represented both the Galvagnion Group and the University of Copenhagen in this year’s DHL Team Run.
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Congratulations to Kristina Mojtic who successfully defended her Masters thesis this week and thereby became a Master of Science at the University of Copenhagen. In her project she investigated the effect of small molecule drugs on the activity of GCase enzyme in differentiated SH-SY5Y cells. Cheers!
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Tuesday evening, Celine Galvagnion gave the Medicinens Verden talk, “What can our skin and brain cells tell us about Parkinson’s?” in front of an engaged and very participating audience at Panum. Thank you all!👌 👏 Céline Galvagnion took us on an instructive journey on how our brain and skin cells can be used to understand the progression of Parkinson’s Disease. This knowledge can be used to design efficient biomarkers and medical treatments against this currently incurable disease that 12.000 people are suffering from, only in Denmark, and so many more worldwide. This was the last talk in the Spring season…
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11.10.2023 Céline received a 131.300 DKK grant from Parkinsonforeningen for the project “Brain glucosylceramide changes associated with disease duration and familial Parkinson Disease.” This project aims to quantify changes in glucosylceramide levels associated with Parkinson’s Disease in post-mortem brain samples.
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We would like to welcome Erasmus students Aiofe Davis & Navya Lalu, Master student Kristina Mojtic, Research assistant Krista Stenstrøm and visiting researcher Soumik Ray to the group!
Galvagnion Group 