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Céline Galvagnion and her partners received a 1.749.377 € collaborative grant from EraPermed for the project “DEEPEN-iRBD Prodromal DEtErminants for PhENoconversion of idiopathic RBD to alpha-synucleinopathies (PD, DLB and MSA)”. The DEEPEN-iRBD study aims to model the progression of REM sleep behaviour disorder (RBD) towards Parkinson’s disease (PD), multiple system atrophy (MSA) and dementia with […]
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Celine gave a talk at the 8th Spring symposium of Center for Medicinal Chemistry on the 25th of May 2023 discussing the lipid changes associated with α-synuclein and Parkinson’s Disease pathology.
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We are excited about Céline being part of the Basic Science Subcommittee in the upcoming World Parkinson Congress that will take place in Barcelona from the 4th until the 7th of July 2023. The World Parkinson Congresses, serve as a global platform where basic scientists, clinical researchers, healthcare professionals, individuals with Parkinson’s, and other stakeholders […]
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We are thrilled to announce that Céline will be joining the FEBS Special Meeting on Sphingolipid Biology as a speaker. The Meeting, scheduled to take place from the 8th until the 13th of October 2023 in Madeira, proposes to summon the sphingolipid community to discuss about the basic principles of sphingolipid biology and about how […]
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Only happy faces after a 100km bike ride in one of the most scenic routes close to Copenhagen! Spend the day enjoying the sun, rejuvenating with a dip in the cold Baltic Sea, eating ice-cream and exploring the sights of Helsingør.
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Using a combination of Small Angle X-ray and Neutron Scattering (SAXS/SANS) measurements, we show that the binding of α-synuclein, the protein involved in Parkinson’s Disease, to negatively charged membranes leads to the fast (<ms) and reversible breakage of vesicles into small, cylindrical and disc-like lipid-protein particles that is followed by a slower (days) and irreversible aggregation […]
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The DEEPEN-iRBD project, funded by @ERANET_PerMed, aims at defining a model for early risk stratification, diagnosis, treatment, and prognosis of patients with iRBD. We are a multidisciplinary consortium of researchers from Luxembourg, Italy, France, Denmark, Sweden and Croatia. The project kick-off meeting took place in Milan on the 27th of February, 2023, where we had […]
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We want to congratulate Frederik Ravnkilde Marlet for successfully attaining his PhD title on February 2023! After 3 years of dedication, perseverance, and tireless pursuit of knowledge, Frederik has emerged triumphant. He has now started his new journey as a Postdoctoral Researcher in the group and is involved in our Lewy body characterisation project.
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Céline Galvagnion received a DKK 113,000 grant from the Danish Parkinson’s disease foundation (Parkinsonforeningen) to continue our work on investigating the interplay between lipid changes and protein aggregation associated with decreases in glucocerebrosidase protein and activity levels in differentiated SH-SY5Y cells.
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We are thrilled to announce that our publication on “Sphingolipid changes in Parkinson L444P GBA mutation fibroblasts promote α-synuclein aggregation” was selected for an article feature at the KU website. We are happy to see our work receiving recognition and being shared with a wider audience. Read the article here →
Galvagnion Group 